Long acting anti-infection constructs on titanium

Long-acting sulfonylureas -- long-acting hypoglycaemia.

long-acting antipsychotics

long-acting (depot) anti-psychotic injection (lai) is an essential component of the treatment of schizophrenia. in this editorial, the journal tries to give a short account of the current ideas and practical aspects of lai, with respect to the iranian experience. two categories of the long-acting injections are discussed mainly regarding their dosage, intervals of their injections and availabil...

LONG-ACTING CONTRACEPTIVE AGENTS: TESTOSTERONE ESTERS OF CYCLOALKYLCARBOXYLIC ACIDS

The synthesis of twenty five esters of testosterone (17β -hydroxyandrost- 4-en-3-one) is described. All esters are derivatives of cycloalkycarboxylic acids. Some of the esters possess α- , β -and/or & - substitution in the ester side-chain. The work was undertaken in order to evaluate long-acting male antifertility effect of such esters. Most of the compounds, especially compound No.1, wer...

Why are long-acting beta-adrenoceptor agonists long-acting?

The extended duration of bronchodilation due to formoterol and salmeterol greatly exceeds that of short acting beta 2-adrenoceptor agonists, such as salbutamol or terbutaline. This extended duration and their capacity to "reassert" airway smooth muscle relaxation in vitro despite repeated washing has prompted considerable debate on the underlying mechanism(s). The comparative pharmacology, and ...

TOXICOLOGICAL STUDIES ON CERTAIN AMINOALKYL ETHERS AS POTENTIAL LONG-ACTING LOCAL ANAESTHETICS

The acute intravenous toxicities of a selection of three potential long-acting local anaesthetics belonging to the series of2- phenoxyethyldialkylamine were determined in mice. Two of the compounds were tertiary amines and the third a quaternary ammonium derivative.The I.V. median lethal dose, (LDso) of one of the tertiary compounds, 21A [N, N- diethyl-2- (2,6- diisopropyl) ethyl amine hyd...